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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Pulsatilité de la sécrétion de LH
© Chasles

Nous mettons en œuvre différentes méthodes permettant de déterminer avec précision l'état endocrinien des individus (dosages immunoenzymatiques, dosages radioimmunologiques...). Dans ce cadre, nous nous intéressons aux principales hormones de contrôle de l'axe gonadotrope (LH, hormones stéroïdes...) ou en lien avec différents facteurs de contrôle interne ou externe (mélatonine, prolactine...). Ces méthodes permettent le dosage dans différents fluides biologiques (sang, urine, fécès...). Ces méthodes sont pour certaines développées via la plateforme de Phénotypage-Endocrinologie de l'unité. Nous mettons également en œuvre des méthodes permettant de manipuler l'état hormonal des individus (pose d'implants...).

Nous utilisons également, dans le cadre de collaborations, des approches reposant sur le couplage chromatographie/spectrométrie de masse pour das analyses supplémentaires.

Ces approches permettent de connaitre avec précision la manière dont les organismes répondent à des variations de l'environnement ou de la physiologie interne pour s'y adapter. Par ailleurs, la connaissance de ces réponses permet la mise au point de systèmes alternatifs aux traitements hormonaux exogènes en élevage.