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31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Infectious Diseases and Public Health

French National Institute for Agricultural Research - University of Tours (France)

Multiresistances and Pathogeny factors from Nematodes

Nematode – Haemonchus contortus L2 larva which have uptaken a solution of fluorescein isothyocyanate (FITC)
© Inra, A. Blanchard
Team leader: Cédric Neveu

Parasitic gastrointestinal  nematodes (GIN) present one of the greatest threats to the productivity and sustainability of ruminant production systems worldwide. In the absence of an efficient alternative strategy, the control GIN population remains largely based on anthelmintics treatments. However, reports of resistance emerged for all anthelmintic classes. Anthelmintic resistance has now become a major concern in veterinary and human medicine since it has spread globally in field populations.

In this context, our main objective is to develop novel strategies for the sustainable control of the GIN impacting livestock welfare and production. Our investigations ranged from the fine characterization of parasite fitness to the functional validation of novel pharmacological targets. For this purpose, we are taking advantage of one of the largest collection of livestock parasitic nematode isolates in the world, including anthelmintic-resistant isolates. 


Pubmed since 2012


Scientific Staff

and Assistant-Engineers


Charvet Claude
Courtot Elise
Harmache Abdallah
Neveu Cédric
Sallé Guillaume

Guégnard Fabrice
Koch Christine
Serreau Delphine

Boisseau Michel
Malsa Joshua
Miclon Morgane