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INRAE

24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

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Infectious Diseases and Public Health

French National Institute for Agricultural Research - University of Tours (France)

Apicomplexa and Mucosal Immunity

Ileal mucosa of Cx3cr1gfp/+ neonatal mice infected by C. parvum. In red C. parvum, in blue nuclear staining, in green Cx3cr1+ cells. CD64 macrophages and Ly6c+ inflammatory monocytes represent the Cx3cr1+ population.
© Inra, L. Potiron
Team leaders: Fabrice Laurent and Sonia Lacroix-Lamandé
Research

Our main scientific objective is to decipher host-pathogen interactions between the parasites Eimeria and Cryptosporidium  in order to deliver new preventive and control methods. These parasites develop in the intestinal epithelium of their hosts. Our strength is to perform concomitantly activities ranging from basic researches on the parasites and on mucosal immunity of young animals in target or model species, to applied research such as immunostimulation strategies, vaccines and xenobiotics.

Alongside, the team has also a strong connection with animal health companies. With these firms, we perform scientific collaborations on alternatives to preventive drug treatments, and numerous service contracts.

Pathogens of the chicken coccidiosis and ruminant cryptosporidiosis are ubiquitous in the environment and these diseases severely impact animal production. Cryptosporidiosis is also a zoonosis affecting young children and immunocompromised individuals and therefore a major ‘One Health’ priority. 

Publications

Pubmed since 2012

Team

Scientific staff

Technicians
and Assistant-Engineers

PhD students

Bussière Françoise
Lamandé Sonia
Laurent Fabrice
Silvestre Anne
Tottey Julie

Lallier Nathalie
Pézier Tiffany
Sausset Alix
Sedano Laura

Fernandez Mégane
Sadrin Guillaume
Tomal Florian
Wenker Janine