Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal logo de l'Université de Tours

Home page

Infectious Diseases and Public Health

French National Institute for Agricultural Research - University of Tours (France)

Bacterial infections and immunity in ruminants

Detection of Mycobacterium bovis in mouse lungs 7 weeks post infection (Modified Ziehl staining,magnification X600).
© Inra, T Cochard
Team leader: Franck Biet

The research activity of the team is dedicated to the study of the main bacterial infections of ruminants including bovine tuberculosis, paratuberculosis and mastitis that have a significant impact on animal and human health worldwide.


The team addresses these diseases along three complementary lines:


  • Phenotypic and functional characterization of inflammatory cells and their interactions with lymphocytes. New approaches for mastitis control by vaccination are also being investigated. Regarding bTB, our main goal is to understand how lung innate cells impact on the protective versus pathological granulomatous response. We approach these questions in the bovine host or mice and also develop original models including bovine cell lines, reconstructed cellular models and Precise Cut Slices
  • Characterization of bacterial cell wall components involved in virulence and immune modulation. This includes LPS of E. coli induced mastitis and cell wall lipids of Mycobacterium avium subsp. paratuberculosis and Mycobacterium tuberculosis complex.
  • Understanding of bacterial evolution during the dynamics of infection and identification of key molecular determinants for fitness, transmission, virulence and persistence in the environment.

Pubmed  since 2012

ProdInra since 2012





Biet Franck
Doz-Deblauwe Emilie
Epardaud Mathieu
Germon Pierre
Gilbert Florence
Rainard Pascal
Remot Aude
Winter Nathalie

Branger Maxime
Carreras Florence
Cochard Thierry
Cunha Patricia
Ferter Maryline
Gitton Christophe

 Védrine Mégane